there are several options. First of all, yes, there is an API when using EPO. So you can query and change TIE reputations. You may do a query to see what content is delivered there.
I have not tested, but you may use the following tools to collect information.
- Convicter – Utilize VirusTotal with TIE/DXL to convict files automatically: There is an script available where you can take a look how the TIE reputation is changed.
- ePO Web API Explorer : Have not checked if this runs with latest EPO versions.
Finally, OpenDXL is available to connect any device to the DXL fabric.
Hope this helps,