I moved this to My Account Online as a better spot for it.
First ensure that your system clock is accurate, date, time and time-zone.
Then right-click your taskbar icon and click Verify Subscription - see if that fixes it.
If not try running the Virtual Technician to see if it fixes the problem.
If that fails to fix it, click that link again and go down to Contact Support and click Contact
You can speak to Customer Service free of charge or use the online chat feature, also free.
I understand that your Virus and Spyware protection is Off. Please check if there are any McAfee updates available by navigating to Updates > Check for updates from the main user interface.