for deploying have to update the McAfee agent to version 4.8 patch 3
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EPO 4.5 is out of Support. You need VSE 8.8 Patch 6 or 7 for Windows 10 Support (KB51111).
Also EPO 4.6 is out of Support: Intel Security Product & Technology Support Lifecycle – End of Life (EOL) – End of Support | Intel Security
New extensions, including actual Product extensions for VSE, are therefore not available for older EPO Versions.
You will have to upgrade to a newer ePO Server Version.