What McAfee product is this?
McAfee File and Removable Media Protection. 5.0.1
Moved from Consumer to Business > Encryption: ePO Managed as a hopefully better spot for people to understand your problem.
If this is not correct I can move it again, simply advise me in a reply here.
When a program access a file, by default the file will be decrypted so the program can read it. For example, if you encrypt a .txt file and attempt to open it with notepad, a key request will be performed and a plaintext version of the file will be presented to notepad. This is the same for all programs unless you set the process as a blocked process in the Encryption Options policy or us the attach encrypted to email for adding an encrypted file to an email.
Alternatively, you can use a self extractor or encrypted ISO for transferring an encrypted file.