It's called Cryptowall so corrected the header and I moved this from Consumer to Business > ePO for better handling.
When these things hit, do not touch any keys or your mouse, power straight off and then back on in Safe Mode and see if a System Restore can be initiated.
That's the advice I give to consumers, however it may be different in Enterprise so will leave that to the experts here.
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But VirusScan didnot detect anything. DAT is most updated version. What I have missed to config in ePO?
It sounds like the answer is nothing. A new variant was released for which there is no current signature. This happens all the time and is not unexpected.
Wipe the system and restore the data from backup, if any. That's about all you can safely do in these situations.