Moved this to LiveSafe.
Make sure your system is totally up to date, including Internet Explorer, even if you never use it. Make sure IE is at default level also as the software relies on it.
Run the Virtual Technician to see if it fixes anything: http://mvt.mcafee.com
If that doesn't help do a complete uninstall/reinstall as in TS101331.
Windows updated today which seemed to fix the problem
That's good news ;-)