I'm confused. What is the name of the policy you created, My Default or a different one? Regardless, you need to ensure that the new policy is applied to the two nodes in question. Since it is only 2 you could do it individually. I'm concerned that the screesnshot you attached is showing us the 2 exceptions to the My Default policy assignment. Essentially showing the opposite of what you intended.
As for the exclusions themselves, ensure that you follow this KB. https://kc.mcafee.com/corporate/index?page=content&id=KB50998
Exclusions for folders and files need to be entered with proper formatting. In the example you gave c:\dir, VSE will actually treat that as a file and not a dir or folder. Folders need to have the trailing slash. e.g., c:\dir\
Hope this helps get you moving forward again.
It did! So i changed my default to the new policy i created. I then changed the pattern from c:\dir to c:\dir\*.*
Is there anyway to tell if this is working from the client side or ePO side?
you can check the exclusions in the VSE console On Access Scanner properties --> default process --> exclusions.