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It is quite possible that a Colleague will pick up this thread,and add to the discussion. As he if I am not terribly mistaken, use ITunes as well.
My itunesprefs.xml file is intact. We had a scare about the same thing a while back and it was a case of the software delaying it because it was acting in an odd way, but not deleting it.
Are you sure it is actually deleted? Is it in the Quarantined and Trusted Items folders? (Navigation > Scroll down).
There have also been long discussions at Apple Forums about it in the past: Why does iTunes delete my itunesprefs.xml? | Apple Support Communities
Thanks Peter As I am 'Unversed' in regards to the subject matter.
It seems to be slightly sporadic - in some cases when I closed ITunes, the iTunesprefs file vanished, and even after a few minutes, it did not return.
In other cases, I saw the file disappear for a few seconds, and then come back again.
As far as I can tell, if I have real time scanning disabled, this issue never happens (tried 3 times and no issue).
I have added the file to my exclude file list in Security Center, but I'm not sure whether this applies to real time scanning or only scheduled scan (and also not sure if this is a good idea as a long term solution)?
FYI - I have been using McAfee for years as it's supplied free with my ISP, and this is the first time I had this issue. I don't think this happened to me back in 2013 when there are other threads on Apple and here about it.
I have also taken a backup of this prefs file and I can copy it in again if it's missing, but obviously that's not an ideal solution.
Not sure what to do - obviously itunesprefs.xml is acting "suspiciously" and the scanner is making doubly sure it's OK and genuine.
On the occasions it doesn't appear with Real-Time Scanning on , is it in the Quarantine folder?
Unless it's in there there's nothing really we can do. It's up to Apple to do their coding correctly (they have a habit of not doing so).
BTW I wouldn't turn off RTS just for this.
Would it be possible to share following log files?
Please zip the contents of these 2 folders and share the same.
It's a bit patchy but it seems better now.
I am still sometimes getting the copyright warning when I open ITunes as if it's the first time I've opened, but, it hasn't deleted my prefs file completely the last few days.
This morning it actually worked fully normally so I am still monitoring it but it may have resolved itself now. Not sure how as I haven't changed anything that I'm aware of.