we didn't experience this behavior, but did you already check VSE logs for errors?
See SNS Weekly Roundup (April 9) for DAT-Reputation and McAfee KnowledgeBase - DAT Reputation Implementation Guide, Rev C for proper configuration. And there you could disable it temporary (or permanently), if you need to.
Moved this thread provisionally to VSE as a better spot for support.
I too have found several servers with 1 to 4 instances of mcdatrep.exe running - those with 4 have CPU pegged. This is "new" behavior - or a new feature, servers are a group of 11 older 2003 - 7 of the group had mcdatrep instances. There had been no evidence of this behavior before 8.8. There is a log file folder which seems like a candidate, but it is empty:
c:\Documents and Settings\All Users\Application Data\McAfee\datreputation\Logs
Only choice I had was to kill off processes but would sure like a better solution.
Thanks for your reply buddy. I have tried to disable process in registry according to the DAT reputation guide https://kc.mcafee.com/resources/sites/MCAFEE/content/live/PRODUCT_DOCUMENTATION/ 25000/PD25481/en_US/DAT_Rep_Implementati…, if you guys also has this incident, please try this.