we have the same error at a customer site with ePO 5.1.2 and RSD 5 (4.7.2 work just fine). Just opened a SR with McAfee.
This is most likely due to the fact that RSD is not supported with the agent 5.0.1. Here is a list of McAfee Agen'ts 5.0.1 compatibility product list:
I would like to know when they plan on supporting RSD with this agent though.
Ah, I mixed up question version und products... nevertheless, the PG only states that you cannot install RSD 5.x on Agent 5.x. AFAIK RSD only sends detections to ePO, which checks these against all known systems.
And just to clarify: we opened a SR because RSD 5.x identified systems as rogue, although they had Agent 4.8 installed.