Quite possibly that's a false positive - Artemis detections sometimes are. But a file with a ".zot" extension comes from ZoneAlarm Mailsafe, and if you're running both McAfee and ZoneAlarm you'll probably have problems - see the ZoneAlarm section below from McAfee's "list of incompatible programs". Some of these are way out of date, but so is the copy of the document that I was using (it still discusses XP).
Whatever. If you've got both McAfee and ZoneAlarm, uninstall ZoneAlarm and see if the computer is behaving any better.
Zone Alarm Anti Virus 2008
Zone Alarm Internet Security 2007
Zone Alarm Security Suite 5.5
Zone Alarm with Antivirus 5.5
ZoneAlarm Anti Virus 2009
ZoneAlarm Extreme Security
ZoneAlarm Free 2012
ZoneAlarm Internet Security 2009
ZoneAlarm Internet Security 2012
ZoneAlarm Security Suite
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