I'm also facing this problem.
Had patch the server on 10th May(after upgrading VirusScan 8.8 Patch 3 to 8.8 Patch 4) and starting from 11th May the issue started.
Almost 1-2 time a week the error will cause the Win2008R2 IIS AppPool to go down 20times now since 10th May and in 2 recent case it do not automatically recover with IISreset or AppPool recycle. Had to manually create a new AppPool to bring up the site.
No problems before this patch was applied and also latest on MS patches as of 27 April.
Hope to get a resolution for this issue.
Thanks and Regards,
Thank you for your answer. You are talking about this article, don't you? McAfee KnowledgeBase - VirusScan Enterprise 8.8 Patch 4 Known Issues
There is one IIS-problem in the list: ... Issue: The W3WP.exe process on web servers may exhibit high CPU after installing VSE 8.8 Patch 4. ...
The thing is: that's not really my problem :-) But I got an answer from McAfee Support and it seems that the hint the guy gave me fixed the problem. You have to modify your VirusScan 8.8 policy and add some exclusions for "On-Access Default Processes Policies", "On-Access Low-Risk Processes Policies" and "On-Access High-Risk Processes Policies":
**\IIS Temporary Compressed Files\
And I added w3wp.exe in "On-Access Low-Risk Processes Policies" as a "Low Risk Process" + uncheck the checkboxes "When writing to disk" and "When reading from disk" (but ONLY for Low-Risk Processes!!!). I made this changes yesterday - no errors since that time. But as I mentioned in my prevoius post it happens spontaneously that the IIS service crashes...So I'll wait 2 more days and let you know if the problem is definitely fixed.
PS: have a look at the VirusScan 8.8 Best Practice Guide for more details: https://kc.mcafee.com/resources/sites/MCAFEE/content/live/PRODUCT_DOCUMENTATION/ 22000/PD22940/en_US/vse_880_best_practic…