Thank you neelima,
I will contact Shriki for more information. However, I still have a lingering question. What if it wasn't a SQL DB? What if it was just a particular application directory? Would MAC be "overkill" or is there a better way?
Mcafee Change Control will provide you with that option. It has File Integrity monitoring capabilties. You can monitor the given application directory for changes by adding the path to the policy. If required, you can also track content for changes along for monitoring.