There are many potential causes for such an error. One possible cause is a greylisitng of one or more McAfee IP's by the server we are attempting to deliver to, however more specifically the error indicates that the recipient server is not responding to our connection attempts for whatever reason, be it a server failure, greylisting, router problem, etc.
Since International-tool.com is the recipient, and is filtered by the SaaS Product, we recommend ensuring that the following IP addresses are allowed through firewalls and whitelisted against greylisting:
-McAfee SaaS IP Ranges-
For further assistance on this, I would recommend contacting the support team that works with your account.
Thanks for replying. We believe the route to our servers are fine from Mcafee as the message is received into the queue as shown in the audit. The error message appears to come a couple of minutes after attempting to send to the server.
I have pasted the message audit details below...
Timestamp Event 2013-09-18 14:58:10 BST Recipient Disposition: [250 Deferred; Mode: normal; Queued: yes; Frontend TLS: yes; SPF: n/a] 2013-09-18 15:00:11 BST Detail: first attempt failure: 451 all mx servers are unavailable for domain international-tool.com
I did see the same error in Message Audit as well. Again, the error indicates that when we attempt to connect to the backend server to deliver the message, the server does not respond within ~30 seconds. The SaaS Product cannot deliver messages if the recipient server does not respond. I recommend reviewing logs on the server and removing any RBL subscriptions that could generate a conflict.
If you need additional logs or further assistance troubleshooting this, I would recommend contacting the support team that works with your account: 1-800-338-8754, Option 2 for Business, Option 2 for Technical Support, and if prompted, Option 4 for SaaS Email Protection.