It's generally not supported to run two AntiVirus security solutions at the same time. If you have a server running ePO only without deploying McAfee security software to that server, I don't see why you couldn't also run Trend Micro.
I have a server running ePO with deploying McAfee security software.
However, i found any workstations with a trial version of Trend Micro Worry-Business.
I will unistall all clients of Trend Micro Worry-Business.