Moved to VSE for better attention.
When you say 'McAfee 8.8 Suite' do you actually mean just the System virus scanning or McAfee Security for Microsoft Exchange v8.0 (aka GroupShield)
If it's just VSE, the problems you experienced were probably down to the access protection prevent mass mailer policy being incorrectly configured or missing VSE exclusions causing performance issues on your mail stores.
VSE 8.8 should work perfectly fine on your server if configured correctly.
The above knowledge base article details configuration and exclusions for VSE and Exchange 2010 but that should apply to Exchange 2013 as well.