This issue occurs when the SuperAgent is on a different subnet than the ePO server and the SuperAgent computer get its IP address via Network Address Translation (NAT).The McAfee Agent binds to the first IP address that it is given during system startup and sends this IP address to ePO. The address given during system startup is not the NAT address. Therefore, ePO can never connect to the SuperAgent.I 'd suggest you to Configure the SuperAgent Repository to be a normal Distributed Repository, using a UNC, FTP, or HTTP path which will be resolved by DNS when doing a replication.
So here's the question, when I press START REPLICATION, which of the above ports is actually being used from the server to the client, 80? 443?
Ans: 443.SPIPE communication with 3DES enryption.