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I administer 10000 workstations running Mcafee VSE 8.5 (the business version) and for an on demand scan with all options checked at (30% CPU) I expect 3-4 hours for a full scan (they are not in use when scan takes place).
These systems dont have 200000 files, maybe 30000 to 50000 max on XP. For 200000 files 4-5 hours even at 100% CPU is very reasonable, you may want to set your scans to run overnight when you are not using them or lower the cpu usage and run them over a longer period.