I'd like to clarify this infomation I provided here.
Q: How is GTI similar/dissimilar than Site Advisor? A: HIPS GTI uses IP address ratings; applies to all traffic in/out of the system.Site Advisor uses domain ratings; has additional functionality that hooks into the browser specifically.
HIPS TrustedSource (GTI) functionality is not just limited to internet browsers. If you are trying to access an IP address rated as HIGH/MEDIUM/UNVERIFIED with other applications (internet browsers, telnet, 3rd party applications, etc.), HIPS can still rate the IP address.