First thing is to check if system is reachable or not using ping
Next, check if C$ and admin$ share is accessible
Make sure also to disable Window Firewall service
Hope this helps.
Are you trying to deploy the Agent using System Tree> Select one Agents> Action> Deploy Agent and then providing the credentials? or using any Agent deployment task etc? Check Server.log at ePO (<Install Dir>\DB\Logs) and Orion.log (<Install Dir>\Server\logs) to see the error in deployment.You should get some clue over there.