Do other CD's open or play normally on your machine?
What operating system and service pack is this and is it totally up to date with Windows Update?
Do you have any other security software installed, if so have you removed it and used whatever removal toold they may offer?
Also are you logged in as an Adminstrator-level user?
THX, I think i got it, i have to turn off window defender in order to install McAfee.
The installer should turn it off automatically anyway. If it doesn't mwork can you answer the other questions I asked?