I've gone through several iterations of iTunes and iOS here and had no issues ever.
Click Web and Email protection
Click Internet Connections for Programs (takes a while to load)
Click the word Program at the top to rearrange them alphabetically and make sure all the following have Full Access (use Edit ifnecessary to change them and don't forget to Save)
Apple Software Update
iCloud (there may be 2 - OK)
If that doesn't help contact Technical Support by phone or online chat, it's free and available through Useful Links at the top of this page.
ok, so i think i believe your confidence in the product working nice with iTunes, however, McAfee must be out of their minds when it comes to pricing. The renewal emails i got say "renew now for $79/yr to protect one system", but when i go to the website directly it says "buy for just $49/yr for 3 systems" !!!
that's crazy, and it makes me want to look elsewhere.
The auto-renewal process for some reason doesn't know aboiut any reduced price sales going on. I would say that's a pretty normal experience in the software world. It's a free market so shop around for the best price. Meanwhile you can turn off the autorenewal on your account page or ask Customer Service to do it for you.