One easy way would be to add that path and any EXE under it to your HIPS Trusted Applications policy. You could probably add the path as follows:
If you wanted EVERYTHING under the Clt-Inst folder to run, including anything in subfolders, you could make one as follows:
Be sure to check the "Trust for IPS" checkbox, and you should be fine.
Please note that ** wildcards should only be used in HIPS 8.0. For HIPS 7.0, only use a single * wildcard character.
KB71522 - Host Intrusion Prevention 8.0 Policy Migration Task adds additional wildcard characters
PD22894 - Host Intrusion Prevention 8.0 for ePO 4.5 Product Guide
Page 72 - FAQ — Use of wildcards in Firewall Rules
PD20106 - Host Intrusion Prevention 7.0.0 for ePO 3.6.1 Product Guide
Page 164 - Use of wildcards