You can exclude files and folders from a manual scan or a scheduled scan but NOT from the real-time (background) scanner. That was a feature of the product about 8 years ago until the powers that be decided the average consumer isn't experienced enough to be trusted & would end up with badly infected machines as a result. I wonder how many of those 45 or so products have full exemptions for real-time protection. I know at least one does but it isn't an antivirus (Malwarebytes). I think you are in error regarding at least Symantec Consumer products as they don't have it either.
It's still part of the Business/Enterprise products which of course involve bulk licensing, VSE or VirusScan Enterprise for example and is something we Moderators have been campaigning to bring back to the consumer product. We've only been partially successful however.
All is not lost if you have enough patience to wait until the lab approves the software being detected. THIS outlines what to do and usually works quickly.