I don't know about the other users but I think a VERY USEFULL feature would be an option at the agent policy to let you choose the subnet an agent would use to report itself to ePO.
I have a lot of servers and workstations with more than one network interface and from time to time an agent pops up with Microsoft's APIPA (169.254.0.0) or an IPv6 address in my system tree.
It messes my tags, sorting criteria and reporting.
There is something similar in the RSD policy that tells the RSD to on listen on interfaces that belong or do not belong to the subnet the user determines.
I could determine in the agent policy that he would only report to ePO it's ip address that belongs to the subnet 10.0.0.0/16. So 169.254.0.0 and fe80:0:0:0:0:0:0:0 would be out.
Let me hear your thoughts!