I had alrady opened a discussion in the past about this problem: https://community.mcafee.com/message/247534#247534
The problem is that our McAfee support has told us to update to Patch 2, this should help...
Well it did not and we are still having this issue with some clients. At the moment we are just scanning the "All local drives" with "Default File Types". In the end it looks like that on a affected system:
Do you have any ideas?