Yes, I did hear some things about ePO 5, but I don't know what info is public (I'm under NDA). What I can tell you is that I'm excited!
Not lucky enough to be under an NDA, but a quick Google turned up: http://www.itwire.com/business-it-news/security/57157-mcafee-pushes-security-con nected-vision
That seems to hint at natural language query ability as one (or the) big new feature. Reports out of the 2012 FOCUS con seem to indicate it's pretty cool. Other stuff points to Windows 2012 support as well.
Let's hope it's a good release!