Moved from Home and Home Office to Business > ePO for better attention.
Until an expert answers I would add that I don't think Windows 8 is supported yet by any McAfee products as it hasn't been released officially.
Also it would help whomever answers this to mention what version of Windows 8 this is (i.e. Windows 8 Release Preview, Windows 8 Pro RTM, x86 or x64 etc. etc.)
8.8 P2 will work, but full support isn't due until P3 (Late this year)
Agent 4.6 P1 and above will work, but full support is yet to be announced:
What makes you think it's VSE that is crashing Windows?