See for detail on my trials with this issue. Here's the short summary:
So, to recap, users with HIPS and Firefox 10 have two options:
* Update their machines to 220.127.116.119 and then get the hotfix (18.104.22.1681) from McAfee tech support and get that deployed
* Modify their ePO policy to disable the "Buffer Overflow" engine while waiting for the above (or a subsequent patch release that incorporates the hotfix).
I am having the exact same problem. So I need to get in touch with McAfee Support to get the HotFix or get Patch 2 if they will give it to me. I looked at he Patch 2 readme and it was published in May 2012 but I don;t see it on my download site. Thanks for the posting!