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I have the same experience with a MS Word App. Slow when mcshield is running or paused, fast when mcshield stopped. What is mcshield doing when it is paused??
I found the problem/solution for my case, and I believe the following happened.
MS Excel is trying to access a registry key that does not exist (for each cell update), and it is opening a read/write lock to the registry. I believed Mcafee adds whole bunch of Event Listener when there is a write request to registry, and those listener are still on even the on-access protection is turned off. So for each cell update, MS Excel do a read/write lock to registry and it triggered the Mcafee event listener that probably cost 1ms. So updating 10k cells last 10 seconds.
I don't know how does it apply to your case but I simply add the registry back and everything is now working fine.
How did you check for the missing registry key? Did this show up in regmon?
1) have you got ScriptScan on?
2) have you updated to the latest version of Windows Scripting Host?
2) Will check.
For the excel problem I had.
Problem exists regardless of ScriptScan on or off.
I have latest windows scripting host
Microsoft (R) Windows Script Host Version 5.7
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I used processmon by the way.
which was the missing registration key in this case?