Sounds like you may want to run an On Demand Scan on that shared folder, as there may be an infection in there. I wouldn't just uncheck the box so that the connection won't be dropped.
I cant tell what share folder has the problem. This server has many shares on it an alot of data. Any hints on how to get the info on what share?
I could be making a dumb assumption that your are managing these VSE systems with ePolicy Orchestrator, but if you do, this is what you should do:
Go into ePO and create a tag, unique to your systems that are file shares.
Tag all your file shares
Create an On Demand Scan task and set it to "Send this task to only computers which have the following criteria" and select the tag that you just created for these systems.
Run the task at your leasure
View the results by creating a threat event query. Filter the query so that it contains only those IP's where you ran your scan. Be mindful though that your results may not show immediately, as On Demand Scans can sometimes take an hour or more to run, depending on the type of system.
I would check back frequently, to see if your query has returned any results. Hopefully the On Demand Scan picks up some detections and erradicates them.
I this you can find the exact file name and location in the on-access logfile of the remote client.
If you are using ePO, you should get some answers in the reporting section.