Make sure you checked in all the extensions that goes with ePO agent 4.6. Also make sure you have a deployment task setup.
Hope that helps.
Thanks for the response.
All extensions were checked in and there is a deployment task to push out the new agent.
Hmmm... I had that same problem a while back. Try doing a force push of the agent to a couple of machines. This will force the agent reinstall and replace the key that ePO has for it.
1.Go to DB folder of ePO & check the server & DB log file. if its ok then
2.deploy the McAfee agent on 1one system & test it. if problem persist then update the mcafee agent 4.6 to patch1 & check.