Yes, this is completely possible When you configure the distributed repository you can choose which packages you wish to replicate - simply select the ones you want.
If bandwidth usage is the concern, though, you might want to have a look at MA 4.6's Lazy Caching option, which is designed for this sort of scenario, and gets round the limitations of only replicating selected packages.
Sounds great, could you point me in the direction of the Lazy Caching? I'm new to ePO!
Brilliant, thanks for the assist.