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It has been a while since I checked, but I think that the current version of MLC is still only officially supported on 2003 server.
The system requirements section of the product guide are a little misleading as they state "Windows Server 2003 Service Pack 1 or greater". But, the "greater" relates to the service pack version, not the version of Server 2003.
If you have a search through this forum I recall seeing a similar article on this same subject and one the McAfee guys may well have posted an alternative installation method which allows it to be installed on 2008. However, it's unlikely this method will be officially supported as I had a 2003 server to call upon, I used it instead of a 2008 server.
Windows Server 2008 support in MLC 2.0
I believe the original issue was reported on MLC 1.0/1.0.1. MLC 1.0 is supported on Windows 2003 server only and it can be installed on 2008 server on compatibility mode.
MLC 2.0 is natively supported on the following OS versions
Windows server 2003 - 32 bit, 64 bit
Windows Server 2003 R2 - 32 bit, 64 bits
Windows Server 2008 - 32 bit
Windows Server 2008 - 64 bit