Am not sure about server\temp but but you can delete the Repo cache folder after stop all the ePO services. Generaly the size of repocache folder increase problem is found in ePO 4.0 .....
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The fact is like you have said, that there have no any negative effects after removing all files from RecoCache folder. thanks alots
and I also have deleted all fils and subfolder from server/temp, it seem also have no any negative effectls.
Am much happy about the problem has been resolved ...... Have a nice day