The problem seems to be cause by port conflict so just which ports are used by this program and check whether they are the same like the ports used by EPO to communicate with the agent :
Also check the SMB ports.
I found the fix.
In Topical Software, Secure Browser.
sLook at setting under the tab administration make sure that "MAKE ALL INTERNET BROWSERS USE LIST" is not checked. McAfee DAT will update with no problems.