System Mechanic Professional 2007 is listed as incompatible in the FAQ's found in the Technical Support pages HERE.
From that I would imagine any version may have problems. I believe it's because it has a protection shield consisting of at least an antivirus, maybe more.
Running more than one antivirus can actually lead you into getting infections.
I made sure not to get System Mechanic Professional.
I would imagine that it still has problems. Registry cleaners generally are a trial and error undertaking as they invariably will remove something important and that particular one has always had issue with various antivirus applications.
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