Apparently it is possible- KB53025
As long as you have agent 4.5 p1 (which you have).
Not done this in a while, but I'm sure you'll have to change the update branch in the agent policy as well.
Thanks. Was able to deploy it via Evaluation branch to two test systems. We recently upgraded from ePO 4.0 and have been longing for this feature. Glad to see after installing ePO 4.6 with ePO 4.5 P1 agent that it now works.