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Sounds like the autoupdate process is running in the background.. Try updating to Patch #14 or later which helps with such issues, and just in case it is a scanning process which is starting up, install the latest 5300 scan engine from the link below:
By the way, to look at the full "On AccessScan Log" on VS 8.0i, check at the path below:
C:\Documents and Settings\All Users\Application Data\Network Associates\VirusScan\OnAccessScanLog.txt
Hope this helps.
Thanks for the follow up. The McAfee Agent Activity Log doesn't show any activity in the 13:00 range for the past few days, so I don't believe the issue to be related to updates. I did look at the OnAccessScan log but, as previously stated, I don't see any scan timeouts around 13:00. I was hoping to find a way to have the On-Access Scanner report everything it has looked at. I'm currently working with our SMS system administrator to determine if software inventories are occurring at that time which would cause McAfee to look at mass numbers of files. If I determine SMS is not performing an inventory at ~13:00, I'll try updating to the most recent patch number and, potentially, the 5300 engine. Thanks again.