I believe your issue should fall under any of the below scenarios:
(A) McAfee will show that, it is not fully secure or (B) McAfee will show a Blank Screen once it is opened.
If it is scenario (A) then do a manual update as shown:
Else if it is scenario (B): Then kindly verify whether you are using any beta version of Internet Explorer, McAfee products are sold as suites and may not work in combination with McAfee Beta products.
If the issue is not resolved by doing a manual, then you need to uninstall & reinstall your McAfee consumer products.
You can use the below link to remove all the installed McAfee products:
http://download.mcafee.com/products/licensed/cust_support_patches/MCPR.exe & you can reinstall the McAfee software back from home.mcafee.com
To have a clear picture of the root cause, you can also go through the following article: http://mcaf.ee/z2nvt