Give a review to event viewer in server, any event must be generated by this issue.
VSE on-access scan depends on the Filter Driver which is the Kernel level driver designed to scan I/O operations.
Maybe the Filter Driver wasn't installed successfully.
Have you tried reinstalling VSE?
Do you manage this server with ePO? Have you checked it's policies?
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Perhaps the server just needs a reboot so that the driver install can finish
we have had this same issue with some of our machines using VSE 8.8