Not a lot to be going on here, but firstly i'd look to IP port conflicts, firewall blocks and making sure the VSE application blocking functionality isn't causing issue.
It would be much easier to fix if it happened every night but seems random. Happens every 3 -5 nights. Not sure why it wouldn't happen every night if it was a firewall or port issue. I've sent MER info to McAfee but haven't heard back.
Also curious to know if anyone else has seen this before.
worked with McAfee and ended up doing a complete uninstall/reinstall. what a nuisance!