Can you boot into "Safe Mode" by tapping F8 repeatedly while booting up? If so try to initiate System Restore to a point prior to this happening. As I don't know what operating system and service pack is installed I can only guess you'll find it under Start/All Programs/Accessories/System Tools.
Seems to be something with the OS,
You can ask someone on the Malwarebytes forums as they are Computer experts. (Most of them. )
You could always try booting into Safe mode by pressing F8, then try using CMD and put "sfc /scannow" without the quotations.
Then try a disk check.