We have such a schema: 1 server (MS 2008 SBS Premium) with AD on it, and 2nd server acting as file-server with software packages to distribute. After installing on the 2nd server ePO 4.5, a problem with software deployment GPO appeared: we got errors 101 and 103 in the System log on every client machine (Windows 7 Professional), source Application Management Group Policy. This begun to happen right after ePO 4.5 installation.
By the way, when we copied software packages to a network share on the 1st server, and assigned GPO to distribute them across our AD, it applied smoothly.
If somebody has the same issue, please advise.