No, McAfee does not support the Microsoft Antivirus API. See KB53813, which specifically states: "There are no plans for McAfee to use the Microsoft Antivirus API."
P.S. That's the second hit when doing a google search for 'Microsoft Antivirus API site:mcafee.com'
I was focussing on the policy setting and found the Microsoft API later when typing this message.
Does someone know what virusscanner supports this API?