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If you have read this thread about Patch 4 you know that it's not an Exchange or Server 2008 only issue. The problem seems to be with the Access Protection (Mass Mailing) policy exclusions of all .exe. So if you do not use this policy, there seem to be no problems. If you do not have problems in your enviroment and use the MM-AP, I would suggest you wait untill McAfee has a solution.
Thanks, I currently do use that policy within ePO, but don't know what the MM-AP is. May just hang fire.
MM-AP is for Mass Mailing Access Protection because exclusions aren't working as they should with patch 4