Yes it's only compatible with Windws XP SP2 or later (x86 only), Vista x86 or x64 & Windows 7 x86 or x64.
There is a VirusScan Enterprise specifically made for Linux: http://www.mcafee.com/us/enterprise/products/system_security/servers/linuxshield .html
Questions regarding that should go here: https://community.mcafee.com/community/business/system/vs-other
With all Enterprise/Business products multiple licensing is required so they tend to be a lot more expensive.
There are probably 30-day trials available however.