Please review the suggestions in this documentRequired Reading - Home User Assistance Malware Troubleshooting which will help you to get your computer back to normal. Please try the Stinger scan mentioned in the document and make sure your windows is updated.
If nothing is getting resolved try this http://www.malwarebytes.org/mbam.php download the free version to a usb stick on a non infected pc and rename the download and installation files to something you can easily remember. Install the program and check for the latest updates and then run the program and let it clean everything it finds and reboot the computer.
Let us know if we would need to proceed further