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Ive found this blog entry which references various MS articles on what to exclude usefull http://myitforum.com/cs2/blogs/scassells/archive/2007/05/14/what-anti-virus-scan ning-exclusions-should-be-considered-for-system-and-servers.aspx
Thanks Tony, l did see that site as well, but saw it was dated in 2007. Just wondering if the information is still correct.
apart from the exchange stuff where if you look on technet there are updated exclusions its pretty good, I always tend to go to technet rather than mcafee for exceptions/exclusions