I am not an MVT expert, but I have moved your post to the MVT area. Hopefully someone can help you with this error soon. :)
Could you please provide more information to narrow down on the issue?
1. Did you run an MVT which was already installed?
2. Downloaded and run MVT fresh from http://mvt.mcafee.com/mvt?
This error can happen while the latest MVT content is being posted to the servers and user runs MVT during that time frame.
Could you run MVT now and update on your findings? If you still have the error, please attach the all the files from %appdata%\mcafee\supportability\
Could you please let us know if MVT is working fine for you now?
I would be more than happy to help you resolve the issue that you are facing.
It keeps saying "multiple instances are not allowed... even though there is only only instance showing in the task manager.
This is an Intel e8400 processor (64-bit) in this machine... could that be an issue?
Message was edited by: HCSHawk on 8/30/10 5:55:03 PM CDT
MVT supports 64-bt so that shouldnt be an issue.
Pl. try uninstalling MVT from add/remove programs, reboot and then install afresh.
Let me know if you still see multiple instances....while trying to run MVT.